FISH and SISH for HER-2 in breast cancer *
REQUESTING AND COLLECTING

Ordering:
FISH for HER2 should ideally be ordered on 'Oncology ISH Request' form

(specialised request form available from Tissue and Molecular

Pathology: (02) 8382 9156 and on the SydPath website).

Medicare item (73332) will fund one HER2 in situ hybridization (ISH)

test of tumour tissue from a patient with breast cancer requested by,

or on behalf of, a specialist or consultant physician to determine if the

requirements relating to human epidermal growth factor receptor 2

(HER2) gene mutation status for access to trastuzumab under the

Pharmaceutical Benefits Scheme (PBS) or the Herceptin Program are

fulfilled (not applicable to public inpatients).

HER2 SISH is usually performed as the triage test, with FISH reserved

for cases which are non-diagnostic or equivocal on SISH.

Collection:
4 unstained 3um sections on coated slides or a paraffin-embedded

block of tumour or cytology cell block.

GENERAL INFORMATION

Availability:
Results available within 7 days of sample arrival in laboratory.

Laboratory:
Histopathology (8382-9223)

Patient Results:
(02) 8382-9100
Synonyms:
HER2 FISH - Breast

HER2 ISH

PathVysion

Ventana HER2 SISH

Clinical Hyperlink:
FISH information page
.
INSTRUCTIONS FOR REFERRING LABORATORIES
Handling & Transport:

The paraffin block will be returned to the requesting laboratory with

the ISH report.
Download ISH request form:
Oncology ISH request form
___________________________________________________________________________________________________________________________________

INSTRUCTIONS FOR HANDLING AT SYDPATH
SydPath Handling:

Data Entry Code:

SydPath Division:
Anatomical Pathology

.

Date/Time published: 30/03/2020 17:34:44
First Previous Next Last