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Phosphate

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Hyperphosphataemia
Hypophosphataemia


Hyperphosphataemia         (top of page) 

Causes:

Factitious
       Delay in separating red cells
Physiological
      Neonates (up to 2.8 mmol/L) and infants (up to 1.8 mmol/L)
Increased Intake
      Oral, Intravenous, vitamin D overdose
Release from Cells
      Tissue destruction, starvation, acidosis, insulin deficiency, malignancy
Decreased Renal Excretion
      Renal failure (creatinine > 0.30 mmol/L), hypoparathyroidism, growth hormone excess
Miscellaneous
      Tumour calcinosis, hypothyroidism, post-menopause.


Hypophosphataemia        (top of page) 

Causes:

Decreased Intake
      Starvation, malabsorption, vomiting, antacids (aluminium hydroxide)
Increased Cell Uptake
      High carbohydrate intake, insulin therapy, alkalosis (especially respiratory)
Increased renal Excretion
      Diuretics, magnesium depletion, fanconi syndrome, hyperparathyroidism
Multiple Causes
      Alcoholism, diabetes mellitus, burns, hyperalimentation
Other
      Inherited causes, paracetamol overdose

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For further information please contact Dr Graham Jones on 8382-9100

gjones@stvincents.com.au

Last updated 17/08/00